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Treatment duration and frequency should be determined by a veterinarian based on the animal's condition

Aging reduces NAD+ synthesis pathways while increasing consumption by enzymes like CD38 and PARPs, activated by inflammation and damage.[13][15] CD38, an immune-related enzyme, ramps up with age, breaking down NAD+ precursors

Mattson and Shea 2003

In a 2018 double-blind trial of 100 depressed patients, 1,000 mcg/day adjunct therapy lifted mood scores by 35% after 3 months, outperforming antidepressants alone

Working with healthcare providers who understand both peptides and hormonal transitions helps optimize protocols