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Description

siRNA was transfected using Lipofectamine 2000 TM Transfection Reagent (Thermo Fisher Scientific) according to the manufacturers protocol

Lycopene (LYC), a potent carotenoid antioxidant, exhibits multiple therapeutic effects, including anti-inflammatory, anti-apoptotic and mitophagy-modulating properties

It has attracted scientific attention due to its purported role in sleep regulation, stress modulation, and neuroendocrine function

The oxidation reaction is mediated by CYP2D6

Similarly, in GV-stage mouse oocytes exposed to vitrification, there is an accumulation of mitochondrial ROS and an elevated rate of apoptosis, both of which are closely associated with mitochondrial dysfunction (47)