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E.Karpel-MasslerG.MayerB.ZolkO.SchmitzB.et al (2021)

Also, key enzymes that consume NAD+ called sirtuins, PARPs, and NAD+ glycohydrolases have distinct roles in aging and age-related diseases

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Indeed, GSH-EE treatment reduced the mROS levels in AS NPCs, as measured by mean fluorescence intensity of MitoSOX ( F (1,14) = 5.14, p 0.99 in posthoc Bonferroni corrected comparisons) (Fig