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All of these steps have an important significance, as indicated above, but the key aspect is perhaps the step via vitamin B12-dependent methionine synthase which links the entire methionine cycle directly to the folate cycle

Because crystalline formulations are better absorbed than naturally occurring vitamin B 12 , patients older than 50 years and strict vegetarians should consume foods fortified with vitamin B 12 and vitamin B 12 supplements, rather than attempting to get vitamin B 12 strictly from dietary sources

Brynne Chandler Author Brynne Chandler is an avid runner, swimmer and occasional weight-lifter who fell in love with all things fitness related while writing TV Animation in Los Angeles

Dosing for pernicious anemia or food-bound cobalamin malabsorption is 1000 mcg/day

[DOI] [PubMed] [Google Scholar] 67.Lefevre C, Jobard F, Caux F, Bouadjar B, Karaduman A, et al