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10.1111/febs.16353 118 KunoA.HosodaR.TsukamotoM.SatoT.SakuragiH.AjimaN.et al (2022)

Standardized protocol development should establish optimal pressure parameters (2.0-2.5 ATA appears favorable based on current evidence), treatment duration (60-90 minutes/session), and session frequency (daily versus alternate day) while addressing implementation challenges such as cost-effectiveness analyses and specialized training requirements for combined CPR-HBO delivery systems (Figure 4)