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Description

Bnip3 mediates the hypoxia-induced inhibition on mammalian target of rapamycin by interacting with Rheb

A boom online has seen unregulated lab-made peptides being touted as a cure-all or quick fix

Melatonin reduces endoplasmic reticulum stress and corneal dystrophy-associated TGFBIp through activation of endoplasmic reticulum-associated protein degradation

Here we report cryo-electron microscopy (cryo-EM) structures of human OCTN2 in a substrate-free inward-facing conformation, a substrate-bound occluded conformation, and an ipratropium-bound inward-facing conformation, revealing how OCTN2 binds and transports carnitine