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It shows a strong correlation with PA (r= 0.51) and PLP in plasma (r= 0.77) and erythrocyte PLP (r=0.73), but a weak correlation with EAST-AC (43, 76)

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Through experiments, we confirmed that MT1G caused changes in GPX4 and SQSTM1, resulting in changes in ARNTL, but EGLN2 was weakly affected

The level of mRNA expression of the transgene in the tissues of the transgenic animals may also be assessed using techniques which include, but are not limited to, Northern blot analysis of tissue samples obtained from the animal, in situ hybridization analysis, and reverse transcriptase-PCR(RT-PCR)