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Abstract Colorectal cancer (CRC) progresses through defined stages, from localized carcinoma in situ (Stage 0) to metastatic disease (Stage IV), with treatment strategies evolving from surgery in early stages to systemic therapies in advanced stages

Personalized medicine approaches are being explored to address these genetic variations and optimize treatment strategies

Sex hormone metabolism is also modulated by the gut microbiota

However, in this study, we performed a comparative trial and the use of compensation values was not necessary

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