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The commenter stated that an FI-AMEI is a prosthetic device because it produces the perception of sound by replacing the function of the middle ear

Positive results from the Phase II WILLOW study and Phase III ASPEN study demonstrate that compared to placebo controls, DPP1 inhibition treatment can significantly extend time intervals to first acute exacerbations in bronchiectasis patients and effectively reduce overall acute exacerbation occurrence frequency (Zhong et al., 2025