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When abnormal results are detected, the interpretation should include an overview of the results and their significance, quantitative results with age-appropriate reference ranges, a correlation to available clinical information, elements of differential diagnosis, recommendations for additional biochemical testing and in vitro confirmatory studies (e.g., enzymatic analysis, molecular analysis), and a phone number to reach the reporting laboratory with additional questions

A random search strategy with up to 1,000 evaluations was employed within each learner-specific parameter space, using AUC as the optimization criterion

van Vliet, A

290 , G1075G1081 (2006)

This patient's lack of primary gastrointestinal malignancies and presence of a parafollicular cell neoplasm make a DNA mismatch repair gene mutation unlikely