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*Correspondence: Vishwanath Venketaraman, [email protected] These authors have contributed equally to this work This article was submitted to Pharmacology of Infectious Diseases, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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In the last decade, SOD1 gained additional roles which are also important to the metabolism of neurons

Zinc ions play a critical role in several metabolic reactions and, when combined with copper, form part of the functional group of key enzymes, such as Cu-Zn SOD and endothelial NOS, which functions to prevent atherosclerosis (153)