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This mechanism is probably designed to hinder the activation of self-reactive lymphocytes directed against autoantigens

Concurrently, comparative studies should intensify on the bioactivity differences between EC parent compounds and their microbial metabolites

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PMCID: PMC2866103

Although no inhibitory action on plasmin activity was observed in rats that were treated with the monomeric compound LSN3353871, administration of the multivalent compound LSN3441732 and LY3473329-HCl salt at pharmacological doses decreased plasma plasmin activity as measured ex vivo (Fig