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When applied in cell culture, asparaginase inhibited cell growth and induced cell death in pancreatic cancer cells

Subsequently, a comprehensive review of the full texts was conducted The study selection process was documented in accordance with the PRISMA 2020 guidelines (Page et al

Under conditions of oxidative stress, elevated levels of reactive oxygen species (ROS) oxidise key cysteine residues in KEAP1 (C226, C273 and C288), altering its conformation, thereby impairing the degradation of NRF2

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However, further epidemiological studies and mechanistic research are required to confirm these results and provide scientific evidence and practical guidance for primary prevention of GDM