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Moreover, ferroptosis is increasingly recognized as an important driver of disease pathogenesis, including but not limited to cancer, degenerative diseases, ischemic injury, and infections [25]

Interestingly, astrocyte reactivity is influenced and modulated by microglia activation, suggesting that drugs targeting microglia may offer an indirect strategy to combat reactive astrocytes

doi: 10.1186/s12866-019-1534-3 162 MilnerEStevensBAnMLamVAinsworthMDihlePet al

More importantly, the iron chelator DFO significantly alleviated renal damage by preventing iron accumulation, alleviating oxidative stress, inhibiting the inflammatory response, and restoring mitochondrial function [257]

Direct eyesight improvement, meaning enhanced visual acuity in healthy eyes or reversal of refractive errors, lacks strong evidence