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The up-regulated and down-regulated pathway scheme as Fig

P -values were calculated for the comparison of all variables using a t-paired test and the Wilcoxon test, and a p -value of 0.05 was considered to be the cutoff for statistical significance

Similar content being viewed by others 1 Introduction Macrophages are vital cellular components of the innate immune system, playing crucial roles in regulating inflammatory responses to maintain tissue homeostasis [1,2,3]

Curr Pharm Des 31(22):17811799 Guo Y, Yang X (2012) System Biology Approach to Study Cancer Related Pathways

Accumulating evidence links such mitochondrial remodeling in females to oxidative stress and altered neuronal excitability as mechanisms through which diverse early-life stressors become biologically embedded, leading to sustained changes in cellular energetics and circuit function [68, 69, 70]