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The major challenge was the exceptional hydrophobicity of the peptide segment, which was overcome by employing a solubilizing tag and optimizing the reaction conditions using hexafluoroisopropanol (HFIP) as a cosolvent

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In addition, the secretory capacity of intestinal epithelial cells (IECs) depends on endoplasmic reticulum homeostasis

The enzyme glutathione reductase regenerates GSH from GSSG using NADPH

Perianal abscess is one of the characteristic complications of Crohns disease