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Future success hinges on identifying CRC-enriched antigens, particularly on TME components (CAFs, CSCs) and leveraging payloads with robust bystander effects to overcome spatial heterogeneity (103)

In certain scenarios, this maximum daily dose differs

Magnesium supplementation, especially when combined with metformin, shows promise in improving metabolic control, reducing inflammation, and potentially preventing complications such as cardiovascular disease and cancer

It is conceivable that to design an MB vaccine potentially functional in any patient independently of the molecular subgroup and stage of development, a good immunogenic antigen should be identified

In these patients, the excess of dietary methionine might even reduce their hyperhomocysteinemia by favoring homocysteine catabolism (Loehrer et al, 1996)