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Levey, A

doi: 10.1007/5584_2016_121

However, the dearth of long-term safety data and the elusive nature of the metabolic pathways of nanoparticles in the brain represent significant obstacles (Zhao et al., 2018)

Furthermore, it has been used as a rescue therapy in vasodilatory shock, where traditional vasoconstrictors may have limited effect (Morelli et al., 2005)

This article explores VIP nasal spray from a research-only perspective, focusing on intranasal delivery mechanisms, bioavailability considerations, experimental use, and safety limitations