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Description

Introduction Chemical inducers of proximity (CIPs) include bifunctional small molecules and molecular glues that induce proximity between two targets, often leading to neomorphic effects that can be leveraged to re-wire biological circuits, which is difficult to achieve with other pharmacological approaches 1,4

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Franzini M, Musetti V, Guarino D, et al

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Oxalate in renal stone disease: the terminal metabolite that just wont go away

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A vaccine targeting the RBD of the S protein of SARS-CoV-2 induces protective immunity

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Despite strong preclinical evidence, further dose-response and clinical trials are warranted

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