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Due to its limited ability to cross the blood-brain barrier, tocilizumab is less effective for ICANS, making glucocorticoids the mainstay of treatment

Simultaneously, small molecule flavin cofactors have been identified as pharmacological chaperones for patients unsuitable for viral therapy

In IV therapy, glutathione is delivered directly into the bloodstream, allowing better absorption and faster results compared to oral supplements

The rate-limiting steps are similar to those of glycolysis in other cell types, with phosphofructokinase-1 being the major regulatory enzyme controlling the rate of glycolysis

Glutathione S-transferase zeta 1 alters the HMGB1/GPX4 axis to drive ferroptosis in bladder cancer cells