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AQP4 on astrocytic end-feet relocates towards the soma, causing astrocyte swelling, capillary compression, and decreased CBF [95,96,97]

Oct 2014;57(3):333-9

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In conclusion, by using quantitative GBCA datasets from both mice and humans, we demonstrated that a deep learning model can, in principle, generate GBCA-equivalent information from a single structural MRI scan for the estimation of regional CBV, and we successfully applied our DeepContrast model to both an in-house aging dataset and a publicly available ADNI dataset from Alzheimer's patients and age-matched controls

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