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The third major target is the selenoenzyme GPx4

Given that you're unlikely to use all 100mg in a single day, this is a critical, practical advantage

10.1136/gutjnl-2020-320633 95 WangF

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Research has found that, conversely, in a streptozotocin-induced type 1 diabetes rat model, reducing FPN levels leads to increased brain iron, causing ferroptosis, and ultimately resulting in cognitive impairment and decline (Hao et al., 2021)