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Cassarino DS, Bennett JP Jr

These detoxifying mechanisms may be phase I detoxifying enzymes such as aldehyde dehydrogenases, alcohol dehydrogenases, aldo-keto reductase, and other enzymes ( The tumor microenvironment is enriched with ROS that have multifaceted roles in cancer cell proliferation, apoptosis, angiogenesis, and metastasis ( GSTA4 cells regardless of increased ROS, implying that inactivation of GSTA4 mildly increases ROS that might promote proliferation

Based on current researched, high PFKP expression is negatively correlated with overall survival in various cancers, including cervical, liver, and lung cancers ( The final step of glycolysis is catalyzed by pyruvate kinase (PK), which converts phosphoenolpyruvate (PEP) to pyruvate and generates ATP

Prothymosin alpha: a biologically active protein with random coil conformation

Our data demonstrate that ABCB7 accommodates two stacked CoPP molecules within the central cavity, in a nearly vertical orientation relative to the membrane (Fig