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MarinescoSjgrens syndrome (MSS) is a rare genetic disorder characterised by cerebellar ataxia caused by degeneration of Purkinje neurons, muscle weakness, hypotonia and ocular cataracts, although several other symptoms have been reported, including bone abnormalities and cognitive impairment

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Studies have continually demonstrated a strong link between a dietary reliance on cyanogenic cassava coupled with general malnutrition, however, these risk factors are present in many regions of sub-Saharan Africa where konzo does not occur 5,24,25

P53-dependent glutamine usage determines susceptibility to oxidative stress in radioresistant head and neck cancer cells