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KLFs, particularly KLF2 and KLF4, are critical shear-responsive transcription factors that maintain the vascular barrier and endothelial quiescence by promoting anti-inflammatory and anti-thrombotic phenotypes and regulating metabolism [200, 201]

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doi: 10.1093/jn/128.12.2334 112

351(1):13-22.) Of the approximately 20 veteran suicides each day, an unknown but significant number are associated with either untreated or inadequately treated PTSD