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SKU: 66067272441
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Description

Shi Y, Massagu J

In line with these findings, Ma Y et al., demonstrated a statistically significant association between rs2242480 with gefitinib trough concentration (C trough ), where the overall interindividual variability was substantial ranging from 47.8 to 470 ng/mL (median 175 ng/mL), where patients carrying the CC + CT genotype had lower C trough when compared to those with the TT genotype ( p = 0.019), suggesting the influence of polymorphism on gefitinib pharmacokinetics [55]