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(2) Balancing Fat Metabolism and Promoting Lipolysis and Energy Expenditure In obesity, the metabolic balance of adipose tissue is disrupted, characterized by enhanced lipogenesis and weakened lipolysis, leading to continuous fat accumulation

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Recently, Pentelute and co-workers developed dimeric proteomimetic TF analogs capable of inhibiting Myc-driven oncogene expression through antagonistic binding to the E-box site 66,67

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and mitochondrial dysfunction is a major source of both ROS and the LIP (75)