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Description

A universal, continuous assay for SAM-dependent methyltransferases

In these experiments, we used a concentration of RSL3 (1 M) that does not completely inhibit GPX4 (Supplementary Fig

Receptors involved in the extrinsic pathway form complexes with caspase 8, triggering apoptosis though the terminal pathway, which is also associated with the intrinsic apoptotic pathway (Medema et al., 1997