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In 10/20 cases DD/ID was reported

Because of similar pharmacological properties, it is reasonable to expect similar risk with the concomitant use of other CNS depressant drugs with opioid analgesics [see PRECAUTIONS, Drug Interactions]

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Because its acetyl shield allows it to bypass the digestive tract and enter the cells intact, it provides an immediate infusion of active, reduced glutathione directly into the cytoplasm