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However, prolonged exposure to such pathological stimuli can drive microglia toward dysfunctional or neurotoxic phenotypes, thereby exacerbating AD progression [8]

doi: 10.1038/s41590-022-01415-8

Vitamin B6: Helps your body fight diseases by making antibodies

31 Because serine is required (1) for the conversion of folic acid to its active form, (2) as a shuttle for methyl groups between the cytosol and the mitochondria, and (3) as a cofactor in the transsulfuration pathway of methionine/homocysteine metabolism, supplementation with betaine should be included with folic acid, cobalamin, and P5P to optimize the interrelated pathways of homocysteine metabolism

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