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Chem Life

Studies in model organisms, particularly yeast, have significantly advanced our understanding of this pathway [38], though some aspects of human ALA biosynthesis remain under investigation

Altering the -carbon stereochemistry (from L to D) can make peptide analogues resistant to some enzymes while still being recognisable by others

Prevotellaceae holds a dual identity: on one hand, many members within the family (e.g., Prevotella copri) are often overrepresented in various liver disease, playing a "bad role" by disrupting the intestinal barrier, producing harmful metabolites, and exacerbating the condition [184]

Moreover, miR-377 expression is markedly upregulated in passaged senescent human skin fibroblasts (HSFs) and can expedite HSF senescence by targeting DNA methyltransferases