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A linear gradient was applied from 2 to 70% mobile phase A over 20 min, followed by an 8-min equilibration step at initial gradient conditions

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By enabling precise genetic modifications, CRISPR offers the potential to correct or suppress genes implicated in pathological responses to IRI, such as oxidative damage, inflammation, apoptosis, and mitochondrial dysfunction [91]

For example, hexokinase, G6PD, aldose reductase, and Na + /K + ATPase showed decreased activity of up to 57% compared to the control lenses, although UV-B exposure did not result in cataract formation (169)

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