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doi: 10.2174/18734294MTE0tNzQbx 82 SeitzKPQianETSemlerMW

Testing helps distinguish low B12 from other common causes of similar symptoms

Gene Set Enrichment Analysis (GSEA): GSEA was performed using the clusterProfiler R package to identify enriched gene ontology (GO) terms associated with storage differences, sex differences, and QTL

This energy-intensive process occurs in the mitochondria, where the increased metabolic activity required to produce ATP inherently generates ROS as a byproduct of the ETC (electron transport chain) [84]