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8 Conclusion Chronic stress may contribute to cognitive dysfunction in ME/CFS by disrupting HPA-axis homeostasis and adversely affecting key cognitive regions such as the hippocampus

doi: 10.3389/fnins.2021.587197 Received 25 July 2020 Accepted 10 February 2021 Published 16 March 2021 Volume 15 - 2021 Edited by Anwen Shao, Zhejiang University, China Reviewed by Yi Yang, First Affiliated Hospital of Jilin University, China

Another study highlighted that synbiotics may modulate the neuroinflammatory markers such as TNF- and IL-6 that are found to be elevated in the case of PD (119)