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doi: 10.1111/rda.12535 112

Moreover, the positive effects of vitamin E supplementation in the treatment of NASH have been documented in several clinical trials 19,20

In a zebrafish NAFLD model, IGFBP7 mediated ferritinophagy through nuclear receptor coactivator 4, thereby regulating ferroptosis and promoting NAFLD progression [212]

Moreover, in both MT1-2 germline KO mice, it has been reported that zinc and MT1-2 are required for bone growth and MT3 is upregulated in the absence of MT1-2 [31]