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H 2 S and pyruvate production with fluorescent probe detection Kinetic H 2 S production was measured using AzMC (Sigma #802409), which is a fluorogenic probe selectively reduced in the presence of H 2 S producing 7-amino-4-methylcoumarin 29 and detectable with excitation wavelength Exc 350 nm and emission wavelength Emi 445 nm

In cancer, aberrant activation of the ERK1/2 pathway often results in enhanced cell proliferation and resistance to apoptosis (Zhang et al., 2020[149]

This results in the inhibition or reduction of the synthesis of the target protein

Its rich composition of basic residues, such as arginine and lysine, makes napin valuable for emulsification and foaming in food applications 21

The association of circulating glutamine levels and depression is still controversial in clinical settings, as our previous meta-analysis reported decreased glutamine levels in MDD patients [22], while unaltered levels were reported in other meta-analyses [48, 49]