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However, replacement of Thr 335 by Ala completely abolished the ability of PKC to bind Pin1 whereas substitution of Thr 335 by the Glu phosphomimetic, reinstated Pin1 binding ( Figure 3D )

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This is a decrease of 4 percentage points from the currently approved estimate of 14 percent in the CY 2024 PFS final rule (88 FR 79443) and currently approved under control number 0938-1314 (CMS-10621)