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That's reassuring for short-term tolerability, but it's two people, not a population

Life (Basel) 13, 1085

Experimental studies conducted in animals over the past two decades consistently demonstrate that disruptions in the light-dark schedule induce inflammatory responses across a range of biological systems, with several findings suggesting potential relevance to BC

It exhibits potent immunomodulatory activity by downregulating pro-inflammatory cytokines such as TNF- and IL-6, while preserving epithelial integrity

Am J Biomed Sci Res 15(2):153177 Travagli V, Iorio EL (2003) The biological and molecular action of ozone and its derivatives: state-of-the-art, enhanced scenarios, and quality insights