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Vavilala et al., 2005)

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ALDH2 variants can slow acetaldehyde clearance, leading to flushing, nausea, and headaches

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We had only 1 Black patient with a TE, excluded due to AIH overlap

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Generally, compound 24 showed no cross-resistance to cisplatin and is obviously no substrate for the ABC-transporters of multi-drug resistant cells

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In 2020, approximately three of four overdose deaths involved opioids, 9 compared with an opioid-related impact of 50% in 1999

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