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Further research may shed more light on the complex relationship between B12 and metabolism

Mi et al., 2024)

Science 370 , 856860 (2020)

For oral dosing: If intermittent doses are given, the maintenance dose is calculated from: Maintenance dose = Dosing rate Dosing interval (11) (See Box: Example: Maintenance Dose Calculations.) Note that the steady-state concentration achieved by continuous infusion or the average concentration following intermittent dosing depends only on clearance