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It also increased dominant follicles and cause better endometrial tissue arrangement [70]

The SGLT2 inhibitor empagliflozin has a beneficial effect in rotenone-induced zebrafish model of PD [146]

Combined with peripheral dopa decarboxylase inhibitors in fixed-dose formulations, it is converted into dopamine after crossing the bloodbrain barrier, effectively compensating for the dopaminergic deficit in the nigrostriatal pathway and significantly improving core motor symptoms such as bradykinesia, rigidity, and tremor [100], long-term use is associated with motor complications including wearing-off phenomena, dyskinesias, and "onoff" fluctuations, as well as peripheral dopaminergic adverse effects such as nausea, vomiting, and hypotension [101, 102]

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