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By principal component analysis of the RNA sequencing data, the differences in gene expression profiles between patients was generally much greater than the differences in gene expression induced by BAT (Supplemental Figure 7A)

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It also induces the reverse transport of these transporters (Sulzer et al., 1995), leading to the release of monoamines from the neuronal cytoplasm into the synaptic cleft (McCann et al., 1998)