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ROIs reactive oxygen intermediates Glucocorticoids on binding to the glucocorticoid receptor (GR), promote the dissociation of heat shock proteins (HSPs), and the ligand-receptor complex translocates to the nucleus then binds to palindromic DNA sequences, called glucocorticoid response elements (GREs)

Following this, the gel was rinsed twice with deionized water and incubated with 0.01% of l-DOPA at 37 C for 4 h for the development of dark-brown color bands by the enzymatic activity of the mh-Tyr