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Glioblastoma (GBM), classified as a WHO IV glioma, is marked by its dismal prognosis, extensive tumor heterogeneity, and the absence of effective treatments, boasting a mere 5-year survival rate of 7.2% [1, 2]

Conversely, high levels of glutathione in the body have been linked to the development of chemotherapy resistance in cancer patients

Toradol injection provides effective relief from pain and inflammation, making it an ideal choice for acute discomfort

EMBO J 30:20442056 Kumar S, Asif MH, Chakrabarty D, Tripathi RD, Dubey RS, Trivedi PK (2013) Expression of a rice Lambda class of glutathione S-transferase, OsGSTL2, in Arabidopsis provides tolerance to heavy metal and other abiotic stresses

By inhibiting the ability of tumor cells to uptake glutamine and increasing the levels of glutamine within the tumor microenvironment, a dual effect can be achieved: suppressing tumor cell growth on one hand and enhancing the availability of glutamine for immune cells on the other hand, thereby strengthening the anti-tumor immune function of immune cells