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Nevertheless, previously, in vivo animal trials had already suggested that NAC could be a good candidate for clinical trials

By supporting cellular resilience, it may help the body respond to the everyday physical demands of an active lifestyle

Key position statements from the ACSM and ISSN both advocate a well-chosen diet containing antioxidant-rich foods such as fruits and vegetables (Reference Thomas, Erdman and Burke16,Reference Kerksick, Wilborn and Roberts53) , which could help mitigate against high levels of oxidative stress in athletes

Given that previous studies have shown that Chac2 can functionally antagonize Chac1-mediated GSH degradation, likely due to its slower catalytic turnover and distinct substrate-binding properties, and supports a model in which CHAC2 competitively binds reduced GSH but degrades it inefficiently, thereby favoring net GSH retention

10.1177/1756285614564152 25 BrackhanM.Arribas-BlazquezM.Lastres-BeckerI