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For individuals sourcing either compound from unregulated online vendors, additional risks include contamination with unknown substances, incorrect dosing due to inaccurate labelling, and the use of non-sterile injection equipment, which can lead to serious infections including abscess formation or sepsis

In addition, subcutaneous semaglutide reduced body weight significantly more than all active comparators tested, while oral semaglutide reduced body weight more than sitagliptin and liraglutide, and to a similar extent as empagliflozin