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Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis

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Treatment of diabetic polyneuropathy with the antioxidant thioctic acid (alpha-lipoic acid): A two year multicenter randomized double-blind placebo-controlled trial (ALADIN II)

Exjade (deferasirox) is the first oral iron chelator approved by the FDA

In addition, it was also confirmed that lactate can induce the formation of MUFAs through the HCAR1/MCT1-SREBP1-SCD1 pathway, which contributes to the resistance of liver cancer cells to ferroptosis induced by oxidative stress (Zhao et al., 2020) (Figure 3)