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Some side effects that may be seen after injectable B12 are: mild diarrhea itching or rash nausea and vomit headache swelling venous thrombosis pulmonary edema or congestive heart failure allergic reaction or anaphylaxis (rare) Caution : Vitamin B12 in the form of cyanocobalamin (found in most dietary supplements) should be avoided by people with Lebers disease (hereditary optic neuropathy), as it can cause severe atrophy of the optic nerve (10)

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Also, it's a good choice for people with low energy levels and small vitamin B12 deficiencies

The symptoms often appear in the hands and feet

Biotechnol Appl Biochem (2023) 70(1):17583