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Since balanced lipid homeostasis is critical for neuronal health, LDs play a crucial role in neurodegenerative diseases

The mechanism involves glycine exerting a hyperpolarizing effect on macrophages and other immune cells, inhibiting calcium influx through voltage-sensitive channels and thereby dampening their inflammatory activity

CBDV acts as an agonist of TRPA1, TRPV1, TRPV2, TRPV3 and TRPV4 channels, and as an antagonist of TRPM8 channels (see Table 2 for references)

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[DOI] [PubMed] [Google Scholar] 185.Iqbal K, Grundke-Iqbal I