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Institutions like the Mayo Clinic and Cleveland Clinic emphasize that while Vitamin B12 for weight loss is popular, theres no strong clinical evidence that injections help shed pounds in people with normal B12 levels

Vitamin B-12 is the source of coenzymes for the respective methylation of homocysteine by 5-methyltetrahydrofolate (5-methylTHF) to form methionine and for the mitochondrial conversion of methylmalonyl-CoA to succinyl-CoA ( Figure 1 )

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